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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Small nucleolar RNA-derived microRNA ： ウィキペディア英語版 Small nucleolar RNA-derived microRNA In molecular biology, small nucleolar RNA derived microRNAs are microRNAs (miRNA) derived from small nucleolar RNA (snoRNA). MicroRNAs are usually derived from precursors known as pre-miRNAs, these pre-miRNAs are recognised and cleaved from a pri-miRNA precursor by the Pasha and Drosha proteins. However some microRNAs, mirtrons, are known to be derived from introns via a different pathway which bypasses Pasha and Drosha. Some microRNAs are also known to be derived from small nucleolar RNA. ==Discovery== Small nucleolar RNA derived microRNA was first described in 2008. The protozoal intestinal parasite ''Giardia lamblia'' lacks the Drosha protein involved in pre-miRNA cleavage from pri-miRNA. However the miRNA processing protein dicer is found in ''Giardia''. A 26 nucleotide RNA, miR2, is processed from the ''Giardia lamblia'' snoRNA GlsR17 by dicer. MiR2 is a microRNA which may regulate the expression of variant surface proteins. Also in 2008, a small RNA was found to be cleaved from SCARNA15, a Human small Cajal body-specific RNA, by Dicer. This small RNA was found to function as a microRNA. Potential microRNAs were also identified in several other Human snoRNAs. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Small nucleolar RNA-derived microRNA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.